New Post: Anyone used the MapWinGIS activeX in a ClickOnce deploy?

We've been exploring this as well. For MW5 we abandoned the click-once workflow because it gives more problems then it solves.
We've been experimenting with the manifest file and it will at least solves the need to register the ocx. Just copying will be enough.
In a short while we'll write a article about it how to do this for your own application.

Thanks,

Paul